Lessons learned from studies on tumor suppression by microcell-mediated chromosome transfer.
نویسنده
چکیده
One approach for identifying chromosomes that carry putative tumor-suppressor genes is the introduction of individual, normal human chromosomes to the tumor cells of interest (1-4). In order to identify human chromosomes that can suppress or modulate tumor-associated phentotypes of tumor cells, we performed chromosome transfer experiments via microcell fusion into cell lines derived from a variety of tumors: neuroblastoma (SK-N-MC), fibrosarcoma (HT1080), uterine endometrial carcinoma (HHUA), renal cell carcinoma (YCR), choriocarcinoma (CC1), uterine cervical carci-
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عنوان ژورنال:
- Environmental Health Perspectives
دوره 93 شماره
صفحات -
تاریخ انتشار 1991